Does Benadryl Show Up On A Drug Test: Don’t Leave Your Result To Chance

Jordan Barnett | Masters in Chemical Engineering
Jordan Barnett | Masters in Chemical Engineering

Over 15 years of experience dodging drug tests.

Does Benadryl Show Up On A Drug Test?

Yes, Benadryl can cause false positive results on a urine screening! It might get flagged as PCP, an illegal hallucinogenic. It can also show up in drug tests as methadone, which is an addictive substance that is used to help with heroin addiction.

Thankfully, beating a urine drug test is a breeze – all you need is high-quality synthetic urine to keep your career on track.

Read on to find out everything you need to know about Benadryl and beating a urine drug test. I’ll even recommend a reliable product that’s been tried and tested by our organization.

doctors doing a lab test

Why Would Benadryl Be A Problem For My Urine Drug Screen?

Benadryl stays in your system for around 48 hours and can cause a false positive drug result via drug screen, especially if you take a high dose. Usually, prescription medications won’t produce a false positive test, let alone a drug like Benadryl which can be bought from most drug stores without a prescription.

False positive drug results can lead to serious consequences, such as:

  • Termination of employment
  • Incarceration
  • Denial of participation from athletic competitions
  • Revoked probation privileges

Further examination via gas chromatography can yield a more accurate and comprehensive outcome. However, the person who took the test may have already suffered some negative consequences from the false positive.

Taking diphenhydramine also has some side effects, such as drowsiness and disorientation. It’s not a good idea to use it too often, but if you’re having a bad allergic reaction to something you ate, Benadryl can provide quick relief. With all that said, it should not be the reason to lose your job!

How Do Urine Drug Tests Work?

It’s important to know how urine tests work and how to beat them, but thankfully your participation isn’t that complicated. You simply pee into a cup and submit it to the examiner. From there, the sample is screened for drugs.

Urine tests typically screen for the following substances:

  • Cocaine
  • Amphetamines or Methamphetamine
  • Heroin or other Opiates
  • Phencyclidine (PCP)
  • Marijuana, THC, or other Cannabinoids
  • Lysergic Acid Diethylamide (LSD)

If you’ve taken Benadryl in the last 48 hours, the urine test can register it as PCP or methadone. This is called a false positive result, and it can mean serious trouble for you. 

Of course, the most effective way to pass a drug test without any risk of a false positive is to give your system enough time to naturally clear itself of diphenhydramine. Given time, your liver will do the job. Unfortunately, most drug tests won’t give you that luxury.

The natural detoxing process can be accelerated by increasing your water intake, but not by much. It’ll still take around two days. If your drug test is scheduled for the day immediately following the announcement, no amount of water can promise a passing result.

Ultimately, it’s best to remove any risk of a false positive altogether by swapping your test sample with synthetic urine. This way, your body’s internal mechanisms are taken out of the equation as you submit a sample that’s guaranteed to be clear of any drugs.

The Right Synthetic Urine For The Job

My recommendation goes to Clear Choice Sub-Solution, and it beats any similar product out there by a mile. 

Why? Clear Choice is completely indistinguishable from regular urine and it can be easily used by men and women. It’s a fantastic product, and the quality is backed up by millions of satisfied users around the US, including yours truly.

Unlike other synthetic urine products, Clear Choice comes in powdered form. You mix it with water on the day of the test to have the solution ready as close to the testing time as possible.

Most synthetic urine products are delivered as liquids and the components tend to separate over time. There’s no telling when a drug test will get announced, so a bottle of the liquid stuff can just go unused for months, only to be ineffective when you need it the most.

You can read up on more information on Clear Choice by heading over to my comprehensive review and user’s guide: Best Synthetic Urine.

Final Thoughts

Diphenhydramine is a perfectly legal drug. You don’t even need a doctor’s prescription to buy it from a drug store! It’s ridiculous to have your job threatened by your allergy medicine. Nip the problem in the bud and stock up on synthetic urine so you’re sure to test clean.